PLT Health Solutions to release new sleep and pain relief ingredient research

PLT Health Solutions will present clinical study results for its Serezin Restorative Sleep + Pain Relief ingredient at the American Academy of Sleep Medicine Conference on June 7–11 in Seattle, Washington, US.

Serezin is a synergistic complex of Boswellia serrata and ginger extracts that have been clinically proven to improve sleep across a wide range of measures. The ingredient helps people get to sleep faster and easier, improves their sleep quality, and helps them wake up easier, more alert, and in a better mood.

“We are excited to present our high-impact research findings at Sleep 2025. We will be showing data demonstrating Serezin improves sleep quality and quantity, but with a special emphasis on the improvements shown within the female-only cohort of our study. While many of us look to tracking devices to understand our sleep, these data often do not align with our experience,” says PLT’s senior clinical research manager, Dr. Salter-Farfan.

“Waking up feeling rested, restored, and refreshed is the defining characteristic of a great night’s sleep. By providing relief for nighttime aches and pain, Serezin unlocks the benefits of restorative sleep so that men and women can have better days, every day,” she adds.

Broad-ranging benefits

A four-week, double-blind, placebo-controlled study was conducted on 60 healthy men and women aged 50–70. Subjects self-reported disturbed sleep due to everyday aches and pains. They received either a 300 mg dose of Serezin a day or a placebo. Measurements were conducted at one, two, and four weeks.

Subjects taking Serezin woke up feeling more rested and restored within the first week. By four weeks, they experienced a 64% greater improvement in restorative sleep than those taking the placebo.

Significant improvements in pain scores started on day seven for the Serezin group. By day 28, subjects taking Serezin experienced a 2.6-times greater reduction in nighttime discomfort and a 75% greater reduction in daytime discomfort compared to the placebo.

With statistically significant improvements by day 14, subjects taking Serezin experienced improvements in getting to sleep that were 85% greater than those taking a placebo. Meanwhile, they reported 93% greater improvements in sleep quality than those taking a placebo, as assessed by the Leeds Sleep Evaluation Questionnaire.

Boosting mood and cognition

Within two weeks, subjects taking Serezin reported having a significantly easier time waking up in the morning and feeling more alert with better motor control upon waking, as assessed by the Leeds Sleep Evaluation Questionnaire.

Mood states were evaluated using a validated questionnaire covering six domains: tension, depression, anger, vigor, fatigue, and confusion. Serezin subjects reported improved overall mood starting onat Day 14. For the study, subjects reported a 2.2-times improvement in overall mood.

“Cognitive health is an intense area of interest and innovation at PLT today, with a broad portfolio that addresses Cognitive Performance, Mental Energy, Stress and Mood, and Sleep and Relaxation,.” According to Steve Fink, PLT Health Solutions ’VP of, marketing, says. He also reveals that for PLT, the company has a growing range of solutions for sleep and relaxation in its ingredient portfolio.

“We have active clinical programs supporting all of these consumer needs,” Fink concludeshe said. “Serezin is an exciting ingredient in the sleep space because it features a different approach to promoting restorative sleep than many of the ingredients on the market today. We feel that this study can help consumer products companies develop compelling, trustworthy messaging for a new generation of sleep support products.”