Webinar preview: Rousselot’s collagen peptides for glucose control and GLP-1 secretion

Modern lifestyles expose people to foods with high sugar levels, disrupting glucose levels and insulin balance, including metabolic wellness. In an upcoming webinar, Rousselot will present how its new ingredient, Nextida GC, could support the well-being of this increasing consumer segment.

Taking place on September 25, 16:00 CEST, registration for the webinar is now open. 

“We have all heard about the ‘Ozempic boom.’ Clearly GLP-1 agonists are becoming a big thing, not only in the US, but we are seeing the trend expanding globally and its influence in the nutraceuticals world,” Florencia Moreno Torres, global marketing manager at Rousselot, tells Nutrition Insight.

“For healthy consumers that would like to begin a ‘GLP-1 journey’ relying on supplements capable of boosting GLP-1 and which bring its benefits — including lowering glucose spikes, improving post-meal response to insulin, and avoiding the ‘glucose rollercoaster’ and sugar crashing — might be a great alternative to use along with a healthy diet and an active lifestyle.” 

Torres notes Nextida GC fits at this moment in the journey. The ingredient is a “specific collagen peptide composition” that clinically shows a natural boost in GlP-1 — lowering post-meal sugar spikes and improving insulin response.

Nextida GC targets GLP-1 secretion post-meal glucose levels

Torres points out that the specific collagen peptides composition in Nextida GC influence GLP-1 secretion and post-eating glucose levels, as observed in a clinical study.

Nextida GC targets GLP-1 production, reducing post-meal glucose spikes by an average of 42%.“The incretin effect is an essential method by which the body preserves balanced glucose levels, involving the secretion of the hormones GLP-1 and GIP, which in turn trigger the production of the most important player in the regulation of our glucose metabolism: insulin.”

“The endocrinological chain reaction unfolds as follows: the rapid entry of glucose into the digestive system following a meal triggers the release of GLP-1 and GIP. This signals the body to increase insulin production, which facilitates the transfer of sugars out of the bloodstream and into the cells, returning glucose levels back to baseline,” she details.

Rousselot created Nextida GC to target an increase in GLP-1 secretion to reduce post-meal glucose spikes by an average of 42%, shares Torres. This was seen in a randomized, double-blind, placebo-controlled, crossover clinical study across a healthy population, including normoglycemic people and people with imbalanced glucose metabolism (prediabetic).  

“At 10 g, Nextida GC yielded a statistically significant GLP-1 increase in the overall healthy population when taken 30 minutes before a meal. The prediabetic subgroup also yielded statistically significant results at both 5 and 10 g.”

“In the same study, Nextida GC supplementation at 5 to 10 g saw up to a 43% reduction in glucose spikes,” she adds.

According to Torres, the results, published in Clinical Nutrition ESPEN, show that this specific supplement can support post-meal glucose control, helping avoid sugar crashes and in turn, potentially reducing side effects like cravings, overeating, and fatigue.

“Additionally, pre-meal insulin levels increased significantly following oral supplementation with Nextida GC, while post-meal insulin levels were lower than placebo. This response allows the body to react more efficiently to the glucose introduced by the meal and lower the subsequent spike without the need for excessive insulin production.”

“High blood glucose after meals can cause cravings and overeating, leading to a cycle of glucose spikes and crashes.With its capacity to improve GLP-1 secretion, support balanced glucose levels, and improve insulin response, Nextida GC’s specific collagen peptide composition could positively influence  from satiety and weight management to mood improvement and stress reduction,” states Torres.

Peaking glucose roller coaster 

Torres warns that feeling a “sugar high” when large amounts of carbohydrates are consumed may indicate a blood glucose concentration spike. “While this high can make us feel momentarily giddy and energized, it is inevitably followed by a ‘sugar crash,’ where tiredness and sluggishness creep in as glucose levels decrease.”

“Scientific studies show that high variability in blood glucose levels after a meal can lead to cravings and overeating, which begins a vicious cycle of glucose spikes and subsequent crashes.”

“These constant fluctuations can negatively affect metabolic health over time,” she adds.

Appealing formats, taste and functionality

Torres highlights that Nextida GC is safe, versatile, and robust and can be used in various applications for a hassle-free supplementary experience. 

Nextida GC enables formulation freedom with instant hot and cold-water solubility, plus it has a neutral taste and odor.

It is also temperature, pH, and shelf life stable as a pure protein ingredient that is sugar- and fat-free. Torres concludes that Nextida GC is easily blendable into various formats for convenience.